Production of blood stem cells from reprogrammed adult cells is notoriously difficult. It emerges that a supportive microenvironment may be crucial for their efficient generation. See Article p.312 ...
Reprogram Biosciences, a preclinical oncology biotechnology company developing mRNA-based therapeutics to treat solid tumors, today announced the close of its seed financing. The close brings total ...
Scientists from Trinity College Dublin have discovered that electrically stimulating macrophages—one of the immune systems key players—can reprogram them in such a way as to reduce inflammation and ...
The ability to make person-specific pluripotent stem cells opens up many possibilities for research tools and perhaps even therapies. But most reprogramming techniques alter cells' genomes, making ...
Reprogram是一家肿瘤细胞重编程技术研发商,向肿瘤内注射mRNA 基因组合,直接在体内(in situ)把肿瘤细胞重编程为抗原呈递细胞(APC),把免疫抑制的肿瘤微环境变成免疫激活位点,触发全身抗肿瘤免疫反应,不依赖外源免疫细胞或广谱药物,让肿瘤 ...
Long-term memory of specific places is stored in the brain in so-called place cells. Neuroscientists have now 'reprogrammed' such place cells in free-roaming mice, by sending electrical impulses ...
Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, according to a study published in Science Advances. Shana Kelley, Ph.D., ...
Embryonic stem cells may spark more vitriolic argument than any other topic in modern science. Conservative Christians aver that the cells’ genesis, which requires destroying embryos, should make any ...